Multiscale Cell-Biomaterials Interplay in Musculoskeletal Tissue Engineering and Regenerative Medicine

Multiscale Cell-Biomaterials Interplay in Musculoskeletal Tissue Engineering and Regenerative Medicine

Multiscale Cell-Biomaterials Interplay in Musculoskeletal Tissue Engineering and Regenerative Medicine is an advanced scientific reference dedicated to the interaction between cells and biomaterials in the repair, regeneration, and engineering of musculoskeletal tissues.

This comprehensive volume explores the latest developments in cell-biomaterial interactions, mechanobiology, scaffold design, stem cell therapies, nanotechnology, bioprinting, computational modeling, vascularization, immunomodulation, and clinical translation. It provides an in-depth foundation for understanding how biomaterials can be designed and optimized to support tissue repair in bones, muscles, joints, and related musculoskeletal structures.

Designed for researchers, graduate students, bioengineers, regenerative medicine specialists, orthopedic researchers, and biomedical scientists, this book is a valuable reference for anyone working in musculoskeletal tissue engineering and next-generation regenerative therapies.

Key Features

• Comprehensive reference on musculoskeletal tissue engineering and regenerative medicine
• Explains the complex interaction between cells and biomaterials
• Covers stem cells, cell-based therapies, in vitro and in vivo models
• Includes advanced topics such as nanotechnology, bioprinting, microfluidics, and computational modeling
• Discusses scaffold design, hydrogels, polymeric biomaterials, calcium phosphate cements, and advanced manufacturing
• Explores mechanobiology, immunomodulation, vascularization, growth factors, and cell signaling
• Written and edited by global leaders in tissue engineering and regenerative medicine
• Essential for advanced study, research, and translational biomedical innovation

What This Book Covers

This book is organized around the fundamentals of cell-biomaterial interactions and the technologies used to design functional musculoskeletal tissue substitutes. Topics include cellular signaling, extracellular matrix recreation, surface modification, chemotaxis, growth factors, vascularization, immunomodulation, mechanobiology regulation, electrical and magnetic stimulation, polymeric biomaterials, hydrogel systems, electrospinning, advanced manufacturing, bioprinting, bioreactors, microfluidics, animal models, and regulatory translation.

Why This Book Is Valuable

Musculoskeletal injuries and disorders affecting bones, muscles, and joints remain a major clinical challenge. This book helps readers understand how modern biomaterials, engineered scaffolds, and cell-based approaches may support tissue repair and regenerative strategies. Elsevier describes the book as covering updated developments and challenges in mechanisms, mechanobiology, structure-function properties, emerging scaffolding technologies, cell engineering, vascularization, and immunomodulation.

For professionals working in orthopedics, tissue engineering, biomaterials, biomedical engineering, and regenerative medicine, this volume offers a strong research-level foundation and a practical overview of emerging translational technologies.

Ideal For

• Tissue engineering researchers
• Regenerative medicine specialists
• Biomedical engineers
• Biomaterials scientists
• Orthopedic researchers
• Graduate and postgraduate students
• Musculoskeletal science professionals
• Cell therapy and stem cell researchers
• Medical and life science libraries

Product Details

• Title: Multiscale Cell-Biomaterials Interplay in Musculoskeletal Tissue Engineering and Regenerative Medicine
• Edition: 1st Edition
• Editors: J. Miguel Oliveira, Rui L. Reis, Sandra Pina
• Publisher: Academic Press / Elsevier
• Publication Year: 2023
• Pages: 918
• Format: Original PDF from Publisher
• ISBN: 9780323918213
• eISBN: 9780323972628